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What is Peritoneal Mesothelioma?
A thin membrane of mesothelial cells, known as the peritoneum envelops
many of the organs in the abdomen.
Peritoneal mesothelioma is a tumor that is on this membrane. Peritonial
mesothelioma’s only known cause is exposure to asbestos, and
because it can lay dormant for many years it is not detected until
the tumor has begun to grow. Peritoneal mesothelioma accounts for
about one-fifth of all mesothelioma cases.
Like any cancer, peritoneal mesothelioma can be either benign
or malignant. Mesothelioma is sometimes diagnosed by chance, before
any symptoms have appeared. The symptoms of peritoneal mesothelioma
typically include abdominal pains, weakness, weight loss, loss
of appetite, nausea, and abdominal swelling.
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Fluid often accumulates in the peritoneal space, a condition
known as ascites. Over time the symptoms can become more
and more severe.
X-rays and CT scans are, typically, the first step towards
detecting peritoneal mesothelioma. The actual diagnosis
or peritoneal mesothelioma is achieved by obtaining a piece
of tissue. The procedure of looking at the peritoneum is
known as a peritoneoscopy and requires anesthesia. If an
abnormality is seen, the doctor will attempt to obtain a
tissue sample - this procedure is called a biopsy. A pathologist
will make a diagnosis by a microscopic analysis of specialized
stains.
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There are at least two explanations for how asbestos fibers can
get into the peritoneum and cause peritoneal mesothelioma. The
first is that fibers caught by the mucus of the trachea and bronchi
are swallowed. Some fibers lodge in the intestinal tract and from
there they can move through the intestinal wall into the peritoneum.
The second explanation is that fibers that lodge in the lungs
can move into the lymphatic system and be transported to the peritoneum.
At this time there are treatments, but no known cure, for peritoneal
mesothelioma. The prognosis depends on various factors, including
the size and stage of the tumor, its extent, the cell type, and
whether or not the tumor responds to treatment.
However, the options for relief and treatment of people with
peritoneal mesothelioma have improved, especially for those whose
cancer is diagnosed early and treated vigorously. Many peritoneal
mesothelioma patients receive a combination of therapies, or multimodal
therapy. Specific types of treatment include chemotherapy and
other drug-based therapies, radiation therapy, and surgery. There
are also clinical trials and various experimental treatments like
gene therapy and immunotherapy, and antiangiogenesis drugs.
Mesothelioma information source: http://www.asbestosresource.com/mesothelioma/peritoneal.html
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